Biostimulators such as Sculptra or Radiesse do not add external volume to tissue — they activate the body's own collagen production. The result develops over weeks, lasts months to years, looks natural. Ideal for patients who desire profound skin improvement without immediate volume increase.
Medically reviewed · Dr. Nusret Fetai · Specialist in Dermatology · 2025
"Biostimulator = hyaluron."
Completely different. Hyaluron fills volume. Biostimulator stimulates own collagen production.
"Works immediately."
Profhilo: 2-4 weeks. Radiesse: 6-8 weeks.
"One session lasts a year."
2 initial sessions in 4 weeks. Refresh every 6-9 months.
Dry skin → Profhilo. Loosened structures → Radiesse.
For mild laxity yes. For pronounced laxity they're preparation.
With anaesthetic cream minimal.
Profhilo: 400-600 €. Radiesse: 500-800 €.
Yes — standard component in DOC360.
Hyaluronic acid fills immediately — lasts 9–18 months. Sculptra stimulates the body to produce its own collagen: results build gradually over 6–8 weeks but last up to 24 months — and work deeper on skin structure.
Ideal from around age 35–40 when early volume and elasticity loss becomes visible — without surgery being appropriate. Especially effective for cheek volume loss, marionette lines, neck and décolleté.
Standard protocols call for 2–3 sessions spaced 4–6 weeks apart, then a refresh after 12–18 months. The exact number depends on your starting point.
Costs depend on product, zone and number of sessions. Guide price: from approx. €400 per session. Individual cost estimate at the free initial consultation.
Yes — with modern biostimulatoren such as Sculptra (poly-L-lactic acid/PLLA) measurable skin tightening is realistic. Results are subtler than a facelift but more natural and lower risk. Dr. Fetai advises honestly: when non-surgical is sufficient — and when a surgical approach would be better.
Biostimulators are not a 'category' — each substance has a precise profile.
Calcium hydroxylapatite microspheres. Works in two stages: immediate volume plus long-term collagen build-up.
CaHA Histology StudiesHigh-molecular non-crosslinked hyaluron with unique thixotropic formulation. Stimulates fibroblasts, keratinocytes and adipocytes simultaneously.
Profhilo Thixotropy ResearchWorks primarily on skin hydration and elasticity. 'Glow + smoothing' rather than volume.
Skinbooster Clinical Data"Biostimulators are investment medicine. One session you don't see immediately — three sessions everyone around you sees. Like strength training."
Biostimulators are the invisible pillar of any serious anti-aging strategy.
After 35, fibroblasts become 'lazy' — collagen synthesis drops 1 % per year. Radiesse & Profhilo wake the cell up.
Two well-combined biostimulators yield 2.3× collagen production.
One biostimulator per year compensates 70-80 % of natural collagen loss over 10 years.
Which layer needs stimulation? With the VISIA skin analysis Dr. Fetai sees porosity, pigment, UV damage — chooses between Radiesse (structure), Profhilo (hydration), Volite (glow), polynucleotides (regeneration).
15 minutes working time, during which we take before photos.
Profhilo: 5 BAP points per face half (ultra-fine needles). Radiesse: deep subcutaneous depots with blunt cannula. 10–15 min pure injection time.
Distribution into layers. With Profhilo: small wheals are gone in 1 hour.
Fibroblasts begin new collagen synthesis. You notice: skin feels firmer, make-up lasts longer, the first compliments wave hits at 4 weeks. Optimal: 2nd session at 4 weeks, then annual refresh.
From cheeks to hands — collagen building where it is truly needed.
Volume loss, sagging, jowls — biostimulatoren build the collagen scaffold from within.
Define and tighten the jawline — not filling, but firming the skin itself.
Gently restore temple volume loss — for more youthful proportions.
Improve skin quality and firmness — poly-L-lactic acid stimulates lasting collagen.
Deep folds from mouth corners — collagen building for more durable results than filler alone.
Rejuvenate ageing hands — Radiesse and PLLA for volume and skin texture.
As a specialist surgeon I command the full spectrum. Honest advice — what truly suits you.
Individual pricing by product, zone and number of sessions. Free initial consultation always.
Privatpraxis · Reine Selbstzahlerleistung
Alle Behandlungen bei Dr. Fetai sind Selbstzahlerleistungen. Keine Kassenabrechnung, keine PKV-Anträge — dafür keine Wartelisten und kein Kompromiss bei Qualität und Technik.
Kostenlose Erstberatung anfragen →Radiesse (Calciumhydroxylapatit) ist ein doppelt wirkender Biostimulator: sofortiges Volumen + langfristige Kollagenstimulation. Dr. Fetai setzt Radiesse gezielt für Handrücken-Verjüngung, Dekolleté, Halsstraffung und Gesichtszonen ein. Haltbarkeit: 12–18 Monate. Kosten: 400–700 € pro Spritze. Selbstzahlerleistung — keine Kassenabrechnung.
Profhilo ist kein klassischer Filler — es enthält hochkonzentrierte Hyaluronsäure (64 mg/2 ml), die in der Haut diffundiert und diese tief hydratisiert und strafft. 2 Sitzungen im Abstand von 4 Wochen. Ideal für: fahle Haut, feine Linien, Hals und Dekolleté, erste Zeichen der Hautalterung ab 35. Haltbarkeit: 6–9 Monate. Kosten: 350–500 € pro Sitzung. Selbstzahlerleistung.
| Aspekt | Profhilo | Radiesse |
|---|---|---|
| Wirkstoff | Hyaluronsäure (64 mg) | Calciumhydroxylapatit |
| Hauptindikation | Hautqualität, Hydratation | Volumen + Straffung |
| Haltbarkeit | 6–9 Monate | 12–18 Monate |
| Preis/Sitzung | 350–500 € | 400–700 € |
Biostimulatoren bei Dr. Fetai: Profhilo 350–500 € pro Sitzung (2 Sitzungen empfohlen), Radiesse 400–700 € pro Spritze, Sculptra 400–700 € pro Flasche. Alle Behandlungen sind Selbstzahlerleistungen — keine Kassenabrechnung, keine Wartelisten. Verbindliche Kalkulation nach persönlicher Beratung, kostenlos und unverbindlich.
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